Brand-name · Dual GLP-1 / GIP receptor agonist (tirzepatide)

Zepbound®

Zepbound® (tirzepatide) once-weekly injection. FDA-approved for chronic weight management and for moderate-to-severe obstructive sleep apnea in adults with obesity.

Starting at$449.99/mo
Zepbound injection pen
Form
Pre-filled injection pen
Frequency
Once weekly
Drug class
Dual GLP-1 / GIP receptor agonist (tirzepatide)

Who is a candidate for this medication?

  • Adults 18+ with BMI 30+, or 27+ with a weight-related condition.
  • Want the FDA-approved brand version of tirzepatide.
  • Comfortable with a once-weekly self-injection.

Who this medication is not for

  • Personal or family history of medullary thyroid cancer or MEN 2.
  • Pregnancy, planning pregnancy, or breastfeeding.
  • History of pancreatitis or severe GI disorders.

Dosage overview

PhaseDose
Weeks 1–42.5 mg once weekly (non-therapeutic starter dose).
Weeks 5+Escalated in 2.5 mg increments no faster than every 4 weeks, up to 15 mg.

Side effects to know about

Common

  • · Nausea
  • · Diarrhea
  • · Vomiting
  • · Constipation
  • · Injection-site reactions

Serious (call your doctor)

  • · Pancreatitis
  • · Gallbladder disease
  • · Kidney injury
  • · Severe hypersensitivity

How your care is monitored

  • Monthly during titration, then quarterly at maintenance.
  • Renal, GI, and gallbladder symptom review at each visit.

Pricing

Zepbound® starts at $449.99/mo. No insurance required. HSA/FSA eligible. Cancel anytime.

Common questions

Is Zepbound covered by insurance?

Coverage varies by plan and indication. Many plans require prior authorization; Eli Lilly offers a savings card for eligible patients.

Ready to see if Zepbound is right for you?

Complete a 5-minute online intake. A US-licensed physician reviews your history and only prescribes if it's safe and appropriate for you.

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