Tirzepatide activates both GLP-1 and GIP receptors, producing greater average weight loss than GLP-1 alone in clinical trials. Compounded versions contain the same active ingredient as Mounjaro® and Zepbound®.

| Phase | Dose |
|---|---|
| Weeks 1–4 | 2.5 mg once weekly. |
| Weeks 5–8 | 5 mg once weekly. |
| Weeks 9+ | Titrated up to 7.5–15 mg based on tolerance and goals. |
Compounded Tirzepatide starts at $249.99/28-day supply. No insurance required. HSA/FSA eligible. Cancel anytime.
In head-to-head trials (SURMOUNT-1 vs STEP-1), tirzepatide 15 mg produced roughly 20–22% average body weight loss vs ~15% for semaglutide 2.4 mg. Individual results vary.
It's a newer, more complex molecule and dual-target formulation.
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