Compounded Semaglutide
Semaglutide mimics the GLP-1 hormone your body already makes, slowing digestion and reducing appetite so it's easier to stay in a calorie deficit. Compounded versions contain the same active ingredient as Ozempic® and Wegovy® and are prepared by licensed US pharmacies.
Who is a candidate for this medication?
- Adults 18+ with a BMI of 30+, or 27+ with a weight-related condition (type 2 diabetes, hypertension, high cholesterol, sleep apnea).
- Ready to pair the medication with sustainable diet and activity changes.
- No history of medullary thyroid carcinoma or MEN 2.
Who this medication is not for
- Personal or family history of medullary thyroid cancer or MEN 2.
- Currently pregnant, trying to conceive, or breastfeeding.
- History of pancreatitis, severe gastroparesis, or active gallbladder disease.
- Type 1 diabetes or diabetic ketoacidosis.
Dosage overview
| Phase | Dose |
|---|---|
| Weeks 1–4 | 0.25 mg once weekly (starter dose to reduce GI side effects). |
| Weeks 5–8 | 0.5 mg once weekly. |
| Weeks 9+ | Titrated up to 1.0–2.4 mg based on tolerance and response. |
Side effects to know about
Common
- · Nausea
- · Constipation or diarrhea
- · Fatigue
- · Injection-site tenderness
- · Reduced appetite
Serious (call your doctor)
- · Pancreatitis (severe, persistent abdominal pain)
- · Gallbladder problems
- · Kidney injury from dehydration
- · Low blood sugar (mainly if combined with insulin or sulfonylureas)
How your care is monitored
- Physician check-in at weeks 4, 12, and quarterly thereafter.
- Weight, blood pressure, and side-effect review at each visit.
- Labs (A1c, lipid panel) reviewed if you have metabolic conditions.
Pricing
Compounded Semaglutide starts at $149.99/28-day supply. No insurance required. HSA/FSA eligible. Cancel anytime.
Common questions
How is compounded semaglutide different from Ozempic or Wegovy?
Same active ingredient (semaglutide) but prepared by a licensed US compounding pharmacy rather than manufactured by Novo Nordisk. Compounded medications are not FDA-approved for safety, efficacy, or quality.
How much weight can I expect to lose?
In the STEP-1 trial, adults on semaglutide 2.4 mg lost roughly 15% of body weight over 68 weeks alongside lifestyle changes. Individual results vary.
Can I stop the medication once I hit my goal?
Your physician will discuss a maintenance or taper plan. Many patients regain weight after stopping, so long-term planning matters.
Ready to see if Compounded Semaglutide is right for you?
Complete a 5-minute online intake. A US-licensed physician reviews your history and only prescribes if it's safe and appropriate for you.
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