Compounded Semaglutide
Semaglutide mimics the GLP-1 hormone your body already makes, slowing digestion and reducing appetite so it's easier to stay in a calorie deficit. Compounded versions contain the same active ingredient as Ozempic® and Wegovy® and are prepared by licensed US pharmacies.
Who is a candidate for this medication?
- Adults 18+ with a BMI of 30+, or 27+ with a weight-related condition (type 2 diabetes, hypertension, high cholesterol, sleep apnea).
- Ready to pair the medication with sustainable diet and activity changes.
- No history of medullary thyroid carcinoma or MEN 2.
Who this medication is not for
- Personal or family history of medullary thyroid cancer or MEN 2.
- Currently pregnant, trying to conceive, or breastfeeding.
- History of pancreatitis, severe gastroparesis, or active gallbladder disease.
- Type 1 diabetes or diabetic ketoacidosis.
Dosage overview
| Phase | Dose |
|---|---|
| Weeks 1–4 | 0.25 mg once weekly (starter dose to reduce GI side effects). |
| Weeks 5–8 | 0.5 mg once weekly. |
| Weeks 9+ | Titrated up to 1.0–2.4 mg based on tolerance and response. |
Side effects to know about
Common
- · Nausea
- · Constipation or diarrhea
- · Fatigue
- · Injection-site tenderness
- · Reduced appetite
Serious (call your doctor)
- · Pancreatitis (severe, persistent abdominal pain)
- · Gallbladder problems
- · Kidney injury from dehydration
- · Low blood sugar (mainly if combined with insulin or sulfonylureas)
How your care is monitored
- Physician check-in at weeks 4, 12, and quarterly thereafter.
- Weight, blood pressure, and side-effect review at each visit.
- Labs (A1c, lipid panel) reviewed if you have metabolic conditions.
Pricing
Compounded Semaglutide starts at $179.99 / 28-day supply. No insurance required. HSA/FSA eligible.
Prescription required. Our licensed provider determines whether treatment is medically appropriate. Medication and dose are not guaranteed. Prices shown apply to the stated supply period and may vary if the prescribed treatment, pharmacy, or product changes.
Common questions
How is compounded semaglutide different from Ozempic or Wegovy?
Same active ingredient (semaglutide) but prepared by a licensed US compounding pharmacy rather than manufactured by Novo Nordisk. Compounded medications are not FDA-approved for safety, efficacy, or quality.
How much weight can I expect to lose?
In the STEP-1 trial, adults on semaglutide 2.4 mg lost roughly 15% of body weight over 68 weeks alongside lifestyle changes. Individual results vary.
Can I stop the medication once I hit my goal?
Your physician will discuss a maintenance or taper plan. Many patients regain weight after stopping, so long-term planning matters.
Ready to see if Compounded Semaglutide is right for you?
Complete a 5-minute online intake. A US-licensed physician reviews your history and only prescribes if it's safe and appropriate for you.
Check If I Qualify — Free & Fast